Menopause symptoms · Ontario

Low mood and depression in menopause

Medically reviewed by Dr. Nathan Roth, MDCM, FRCSC, FACOG · Updated 2026-11-01

Can menopause cause depression or low mood?

The menopause transition is a window of increased vulnerability to depressive symptoms, especially with prior depression, severe hot flashes, or major life stress. Low mood is medical — not a character flaw. Treatment may include psychotherapy, antidepressants, treating sleep/flashes, and sometimes HRT for eligible women with concurrent vasomotor symptoms. HormoneFit screens mood as part of menopause care.

  • Prior depression raises risk in perimenopause
  • Treating flashes and sleep often lifts mood
  • SSRIs/SNRIs can treat mood and some vasomotor symptoms
  • Suicidal ideation needs urgent local/emergency care

Assessment

Distinguish adjustment stress from major depression. Screen for anhedonia, sleep, appetite, concentration, and safety. Rule out thyroid disease and medication effects when appropriate.

Treatment

Evidence-based psychotherapy and antidepressants remain foundational. HRT is not a stand-alone antidepressant but may help when vasomotor symptoms drive distress in eligible women.

Anxiety and mood guide

References & guidelines

  1. The Menopause Society — mood and menopause
  2. SOGC — women’s mental health in midlife

Educational only — not personal medical advice. Virtual HormoneFit visits are private-pay membership care. In-person OHIP-insured consultations are arranged separately when medically indicated. Book a virtual visit or view care plans.

Ready to take the next step?

Schedule your first visit to discuss your symptoms and goals with a licensed specialist. We'll help you explore your options and tailor solutions to your midlife health.

You can also check out our FAQ.

Find relief that works for you

Learn about our evidence-based care options and tailored approaches to help you feel like yourself again.

Take control of your midlife health with a plan that works for you.