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Why is progesterone used in HRT?

Medically reviewed by Dr. Nathan Roth, MDCM, FRCSC, FACOG · Updated 2026-07-26

Why is progesterone used in HRT?

If you have a uterus and take systemic estrogen, a progestogen (such as micronized progesterone) is added to protect the endometrial lining from overstimulation. Women without a uterus often use estrogen alone. HormoneFit individualizes progesterone type, dose, and schedule for Ontario patients.

  • Protects the endometrium when systemic estrogen is used
  • Micronized progesterone is a common bioidentical option
  • May help sleep for some women when taken at night
  • Side effects can include spotting, breast tenderness, or mood changes
  • Not always required after hysterectomy

Choosing a regimen

Continuous combined vs cyclic regimens depend on bleeding preference and stage of menopause. Discuss options on our estrogen therapy page or book a visit.

Related HormoneFit resources

References & guidelines

  1. NAMS Hormone Therapy Position Statement
  2. SOGC

This page is educational and does not replace personalized medical advice. HormoneFit physicians assess each patient individually. Women in Ontario can book a virtual consultation.

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